PETATIS REAGENT

PETATIS REAGENT - Names and Identifiers

Name	Bis(cyclopentadienyl)dimethyltitanium
Synonyms	PETATIS REAGENT DIMETHYLTITANOCENE BIS(CYCLOPENTADIENYL)DIMETHYLTITANIUM Bis(cyclopentadienyl)dimethyltitanium BIS-(CYCLOPENTADIENYL)-DIMETHYLTITANIUM(IV)
CAS	1271-66-5

PETATIS REAGENT - Physico-chemical Properties

Molecular Formula	C12H16Ti
Molar Mass	208.14
Storage Condition	-20℃
Refractive Index	1.49
Use	Overview bis-cyclopentadienyl dimethyl titanium may be used as a methylenating agent for carbonyl compounds. Dicyclopentadienyl dimethyl titanium has many advantages such as easy preparation, simple operation, wide range of reaction and so on. It is applicable to a variety of carbonyl compounds, including aldehydes, ketones, esters, lactones, and readily enolated ketones and more acidic substrates. This reagent is very effective for the methylene reactions of alkyl ketones, aryl ketones and cyclic ketone compounds, although it yields only moderate yields for the reaction of aldehydes.

PETATIS REAGENT - Risk and Safety

Hazard Symbols	Xn - Harmful F,Xn,F -
Risk Codes	R67 - Vapors may cause drowsiness and dizziness R65 - Harmful: May cause lung damage if swallowed R63 - Possible risk of harm to the unborn child R48/20 - R38 - Irritating to the skin R11 - Highly Flammable
Safety Description	S62 - If swallowed, do not induce vomitting; seek medical advice immediately and show this container or label. S46 - If swallowed, seek medical advice immediately and show this container or label. S36/37 - Wear suitable protective clothing and gloves.
UN IDs	1993

PETATIS REAGENT - Upstream Downstream Industry

Raw Materials	Titanium, chlorobis(h5-2,4-cyclopentadien-1-yl)methyl- Titanocene dichloride Methyllithium Methylmagnesium Bromide Titanium tetrachloride 1,3-Cyclopentadiene Methylmagnesium chloride Trimethylaluminium
Downstream Products	Titanium, chlorobis(h5-2,4-cyclopentadien-1-yl)methyl- Titanocene dichloride Methyllithium Methylmagnesium Bromide Titanium tetrachloride 1,3-Cyclopentadiene Methylmagnesium chloride Trimethylaluminium

PETATIS REAGENT - Nature

refractive index	1.49
storage conditions	Freezer (-20°C)
water solubility	SLOW hydrolysis

Last Update：2024-04-10 22:29:15

PETATIS REAGENT - Preparation

At -10°C, slowly add Et2O solution of methyl lithium (1.6M,47.3mL,76mmol)(20 minutes) to titanium dichlorocene (33.3mmol) in a suspension of anhydrous toluene (100mL), and stir the mixture at the same temperature for 45 minutes. The reaction mixture was added (via cannula) to a solution of ammonium chloride (1.2g) in water (24ml) cooled to -10°C. The two phases are separated, the organic layer is washed with cold water (3 × 20ml) and salt water (1 × 20ml), dried by sodium sulfate, filtered and concentrated under reduced pressure to 60ml, which contains dicyclopentadienyl dimethyl titanium.

Last Update：2024-04-10 22:29:15

PETATIS REAGENT - Security information

dangerous goods mark	Xn-F,Xn,F
hazard category code	67-65-63-48/20-38-11
safety instructions	62-46-36/37
dangerous goods transport number	1993
HazardClass	3
PackingGroup	II
customs code	29310099